Microscopy Matters

Insights from the Advanced Imaging Center at Janelia

February 12, 2016
by Jesse Aaron, Ph.D.
Comments Off on Multi-Color Single Molecule Localization Microscopy (SMLM)

Multi-Color Single Molecule Localization Microscopy (SMLM)

Introduction In a previous blog post, we discussed probe selection for single molecule localization microscopy (SMLM) techniques such as PALM and STORM. This class of techniques is powerful in that it can achieve some of the highest spatial resolutions (in … Continue reading

May 8, 2015
by Jesse Aaron, Ph.D.
Comments Off on Probes for Single Molecule Localization Microscopy

Probes for Single Molecule Localization Microscopy

Background The last 10 years has seen an explosion of techniques aimed at creating biological fluorescence images with unsurpassed clarity via super-resolution microscopy. Among these various techniques that circumvent the diffraction barrier, there is a group of methods that can … Continue reading